Celebrating Four Years on Pomalidomide

This month is the fourth anniversary of my start in the pomalidomide study, and today is the end of the 52nd 28-day cycle. The news is pretty good.

Bones: Because calcium has been a little high lately, suggesting a possible bone issue, we did a skeletal survey and a bone density scan today. Quote from bone survey report: "Generalized spotty osteopenia without localized lytic lesions. No change since 3/4/09." That works for me! Although x-ray doesn't always show myeloma lesions, this report means that I probably do not have a bone on the verge of breaking. Furthermore, the bone density measurements were the same as two years ago, within the measurement accuracy of the DEXA system, so my overall bone health is good. That's all good news. I do not take Fosamax, but I do take Vitamin D3 and Vitamin K2 (not Vitamin K).

Cancer markers: IgG dropped significantly, from 1280 to 1100 mg/dL, and M-spike obediently followed, dropping from 1.1 to 1.0 g/dL, where it hasn't been since last September. That's very nice. I doubt it's a trend, but wouldn't that be great? Lambda light chains are up, from 1.99 to 2.80 mg/dL, but kappa chains are up too and anyway I'm not sure that light chains are an important marker in my particular myeloma.

Other: Calcium is still high, at 10.3 mg/dL, but that could be a lingering effect from the marathon last Sunday. Some dehydration happens in a marathon, like it or not, and recovery takes a while. Liver markers are at the top of the reference range, too, but we might attribute that to the marathon as well. Neither is an issue right now. Both the red blood cell count and the white cell count are a bit lower than usual though, and I don't know what to think of that. We'll see what they do next month. Actual counts are shown below.

Doctor L:

Most-Recent Test Results:

Test    Dec 14    Jan 12    Feb 07    Mar 08     Remarks
M-spike g/dL 1.1 1.2 1.1 1.0 \ Tumor marker
IgG mg/dL 999 1190 1280 1100 / Tumor marker
Lambda mg/dL 3.15 2.24 1.99 2.80 L Free light chains
Calcium mg/dL 10.3 10.0 10.2 10.3 High
Creatinine mg/dL 1.1 1.0 1.0 1.0 Kidney, OK
HGB g/dL 15.1 15.1 15.2 14.2 Hemoglobin, OK
RBC M/uL 4.17 4.36 4.18 3.86 Red cells, low
WBC K/uL 4.8 4.8 4.5 3.7 White cells, low-norm
ANC K/uL 1.90 2.40 1.70 1.50 Neutrophils, low

Related Links:

My Myeloma     A discussion of my myeloma, not very technical.
My Treatment History Not technical.
My Test Charts Graphic displays of several key test results over time.
My Test Result Table Somewhat technical. Best with a wide browser window.
My Supplement Regimen With links to where I buy them.